Of course, "better" is subjective. Using v1.0.0.17 on the wrong executable (like the 2007 SourceNext version or the 2014 Ultimate HD Edition) will result in crashes. You need the specific original GameCube-to-PC port executable. Furthermore, expect anti-virus false positives—trainers modify memory in ways that heuristic scanners dislike.
: For older versions of the game (like the 2005 original or UHD edition), some trainers like the Razor Trainer require replacing the game's .exe file with a modified one to function. Best Practices for Use resident evil 4 trainer v 100 17 better